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What is Nicotinamide Riboside Chloride (NR) CAS 23111-00-4?

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What is Nicotinamide Riboside Chloride (NR) CAS 23111-00-4?
June 02, 2020 10:27AM
What is Nicotinamide Riboside Chloride (NR) CAS 23111-00-4?

Nicotinamide riboside, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. NR blocks degeneration of surgically severed dorsal root ganglion neurons ex vivo and protects against noise-induced hearing loss in living mice. Nicotinamide riboside prevents muscle, neural and melanocyte stem cell senescence. Increased muscular regeneration in mice has been observed after treatment with nicotinamide riboside, leading to speculation that it might improve regeneration of organs such as the liver, kidney, and heart. Nicotinamide riboside also lowers blood glucose and fatty liver in prediabetic and type 2 diabetic models while preventing the development of diabetic peripheral neuropathy. Note: Nicotinamide Riboside chloride is a α/β mixture.To get more news about Nicotinamide Riboside Chloride (NR), cofttek official website is the best place for you.

Nicotinamide Riboside Chloride (NR) nucleosides are precursors of nicotinamide adenine dinucleotide (NAD) and represent a source of vitamin B3. Recent studies have shown that taking in a greater amount of nicotinamide nucleosides naturally present in foods can provide new health benefits. For example, nicotinamide nucleosides have been implicated in increasing tissue NAD concentration and inducing insulin sensitivity as well as enhancing sirtuin function. Its ability to increase NAD production suggests that nicotinamide nucleosides can also improve mitochondrial health, stimulate mitochondrial function, and induce the production of new mitochondria. Other studies using nicotinamide nucleosides in the Alzheimer’s disease model have shown that the molecule is bioavailable to the brain and may provide neuroprotection by stimulating brain NAD synthesis..

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